Description
This product is prepared for LABORATORY RESEARCH USE ONLY and may not be used for other purposes.
KPV Peptide
For Laboratory Research Use Only
What is KPV?
KPV (Lysine–Proline–Valine) is a naturally occurring tripeptide derived from the C-terminal end of alpha-melanocyte-stimulating hormone (α-MSH). While α-MSH is known for its anti-inflammatory and immune-modulating effects, KPV retains these properties in a much smaller and more stable structure—making it an attractive candidate for research into inflammation, immune function, and gut health.
Unlike full-length α-MSH, KPV does not activate melanocortin receptors associated with pigmentation, allowing researchers to explore its benefits without those side effects. Its unique profile has made it a focus in studies related to inflammatory bowel diseases, wound healing, skin conditions, and autoimmune disorders.
Key Research Areas
1. Anti-Inflammatory Effects
KPV has been shown in multiple studies to suppress the production of pro-inflammatory cytokines such as TNF-α, IL-6, and IFN-γ. It can reduce inflammation both locally and systemically, making it highly valuable in models of chronic inflammation and immune dysregulation.
2. Gut Health and Inflammatory Bowel Disease (IBD)
Research suggests KPV may protect and restore the intestinal lining, helping reduce symptoms in experimental colitis models. Its ability to cross cell membranes and deliver anti-inflammatory effects directly to epithelial cells makes it especially promising in gastrointestinal research.
3. Skin Repair and Dermatology
Topical applications of KPV in research have shown accelerated wound healing and reduced inflammation in models of dermatitis, eczema, and psoriasis. Its ability to work without pigment-related side effects gives it an advantage over α-MSH analogs.
4. Immune Modulation
KPV interacts with the melanocortin 1 receptor (MC1R) and exhibits immunosuppressive activity without broadly suppressing the immune system. This makes it a candidate for autoimmune research models and studies involving cytokine regulation.
Product Specifications
| Attribute | Details |
|---|---|
| Product Name | KPV Peptide (Lys-Pro-Val) |
| Quantity | 10mg per vial |
| Form | Lyophilized Powder |
| Molecular Formula | C17H32N6O4 |
| Molecular Weight | 384.48 g/mol |
| CAS Number | 413604-97-6 |
| Synonyms | α-MSH (11-13), Tripeptide KPV |
| Purity | >99% (Verified by HPLC) |
| Storage | Store at -20°C; keep sealed and protected from light and moisture |
| Reconstitution | Soluble in sterile water or bacteriostatic saline for research applications |
| Research Uses | Inflammation Studies, Gut Health, Skin Research, Autoimmune Disease Models |
Legal Disclaimer
This product is sold strictly for laboratory research use only. It is not a drug, food, or cosmetic and must not be used for human or veterinary purposes. It is the buyer’s responsibility to ensure that use and handling of this material complies with relevant laws and regulations.
Safety Information
- Not for human consumption or therapeutic use.
- Must be handled only by trained professionals in a controlled research environment.
- Improper use may result in health risks or violations of your institution’s policies.
Educational Note
All data and content provided are for educational and informational purposes only. The U.S. Food and Drug Administration (FDA) has not evaluated this compound, and it is not approved to diagnose, treat, cure, or prevent any medical condition.
