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GHRP-2 (5mg)

$42.00

5mg per vial

 

Container: Glass Vial
Presentation: Lyophilized Powder
Molecular formula: C45H55N9O6
Molecular weight: 817.97 g/mol
PubChem CID: 5486808
CAS Number: 158861-67-7
Synonyms: GHRP-2 Acetate

Pralmorelin

KP-102

Growth Hormone-Releasing Peptide-2

Research Applications: Growth Hormone Release

Appetite Regulation

Muscle Growth

Bone Density

Neuroprotection

 

Description

This product is prepared for LABORATORY RESEARCH USE ONLY and may not be used for other purposes.

 


What is GHRP-2?

GHRP-2 (Growth Hormone-Releasing Peptide-2) is a synthetic hexapeptide designed to stimulate the secretion of growth hormone (GH) from the pituitary gland. It belongs to the family of growth hormone secretagogues and acts by binding to the ghrelin receptor (also known as the growth hormone secretagogue receptor, GHSR). Unlike some other peptides, GHRP-2 not only increases GH release but also mildly elevates levels of prolactin, cortisol, and adrenocorticotropic hormone (ACTH), distinguishing it from more selective agents like ipamorelin. This broader hormonal effect makes GHRP-2 a unique tool for studying GH-related pathways and their downstream physiological impacts.


GHRP-2 and Growth Hormone Release

GHRP-2 functions as a potent growth hormone secretagogue by activating the ghrelin receptor in the pituitary gland and hypothalamus. This binding triggers a signaling cascade that amplifies the pulsatile release of GH. Research has shown that GHRP-2 can increase GH levels significantly in various animal models, making it a valuable compound for exploring GH dynamics. Its mechanism differs from growth hormone-releasing hormone (GHRH) analogs due to its interaction with the ghrelin receptor, offering a complementary approach to studying GH secretion.


GHRP-2 and Appetite Regulation

One of GHRP-2’s notable effects is its ability to stimulate appetite, a property linked to its ghrelin receptor agonism. Ghrelin, often dubbed the “hunger hormone,” plays a key role in energy homeostasis and food intake. Studies in animal models have demonstrated that GHRP-2 administration can increase food consumption, making it a useful tool for research into appetite regulation, obesity, and metabolic disorders.


GHRP-2 and Muscle Growth

Research suggests that GHRP-2 may support muscle growth and repair by enhancing GH release, which in turn promotes protein synthesis and nitrogen retention. In studies with rats, GHRP-2 has been shown to counteract muscle loss in catabolic states, such as those induced by glucocorticoid treatment. While human data is limited, its GH-stimulating properties position GHRP-2 as a candidate for investigating anabolic processes and muscle maintenance in controlled research settings.


GHRP-2 and Bone Density

GHRP-2’s influence on GH secretion may extend to skeletal health. Elevated GH levels are known to stimulate osteoblast activity and bone formation. In preclinical studies, GH secretagogues like GHRP-2 have been associated with increased bone mineral density in rodents, suggesting potential applications in bone metabolism research. These effects are likely tied to GH’s role in regulating insulin-like growth factor-1 (IGF-1), a key mediator of bone growth.


GHRP-2 and Neuroprotection

Emerging research has explored GHRP-2’s potential neuroprotective effects. By modulating GH and IGF-1 levels, GHRP-2 may influence neuronal survival and repair mechanisms. Studies in animal models of brain injury have indicated that GH secretagogues could reduce oxidative stress and inflammation, highlighting GHRP-2 as a candidate for neuroscience research focused on neuroprotection and recovery.


GHRP-2 as a Research Tool

As a ghrelin receptor agonist, GHRP-2 serves as an effective probe for studying ghrelin-mediated pathways. Its ability to stimulate GH release, appetite, and other physiological responses makes it a versatile compound for investigating metabolic, endocrine, and neurological processes. Researchers have also used GHRP-2 to explore its potential in developing novel therapeutic agents targeting the ghrelin receptor.


Legal Disclaimer

This product is sold as a pure research compound and is not intended for human consumption or use as a dietary supplement, drug, or treatment. It is provided solely for laboratory research purposes and must not be used for diagnostic or therapeutic purposes, in food, cosmetics, or any medical applications.

The statements on this website have not been evaluated by the U.S. Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease or medical condition. All products are for research and development use only.


Important Safety Information

– Keep this product out of the reach of children.
– Limited research is available on this material, and improper handling or use may pose risks or result in adverse effects.
– This product is sold solely as a raw material for research purposes, and its purity and quality are attested exclusively for these purposes.
– It is intended for handling only by qualified researchers with the necessary knowledge and equipment to safely manage such materials.

By purchasing, you agree to indemnify Molecular Solutions Peptides against any adverse effects that may arise from improper handling or use of this product.


Educational Notice

All information on this website is provided solely for educational purposes. These products are not pharmaceuticals or medications. The Food and Drug Administration (FDA) has not approved them for the treatment, prevention, or cure of any disease, medical condition, or ailment.

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